47M, 14 weeks on tirzepatide 7.5 mg, down 17 lb, lifting 3x/week. Recovery has been the bottleneck, so I looked into PEG-MGF. The human data are thin, mostly anecdotal, and I’m not comfortable guessing at frequency or timing—especially with the extended half-life and unknowns around tissue proliferation.
My pragmatic take: until there’s credible body-composition or safety data in people, it’s a hard no for me. I’m sticking with protein, sleep, and deload weeks. Curious if anyone here has tracked objective metrics on it—DEXA, labs, lifts—and actually seen something repeatable?