I’ve been reading NCT04184622 — 2,539 people, placebo vs 5 mg, 10 mg, and 15 mg tirzepatide, Week 0 to Week 72. I’m around my own week 72 now and realized I tracked weight but almost nothing else.
For those further along, what non-scale markers actually mattered? Waist, fasting glucose, A1c, resting heart rate, appetite scores?
Not asking for dosing advice, just trying to build a better personal spreadsheet for the next stretch.
Waist and resting HR. Weight stalled but waist kept moving.
Resting HR is underrated. Mine dropped a few bpm by week 72 even in a month the scale didn’t move.
Only logged weight. Wish I’d added fasting glucose and A1c.
A1c is useful, but a daily hunger score explains my stalls better. I use 1 to 5 before dinner.
The hunger score thing is smart. Did you start before or after week 72? Reconstructing mine is all vibes.
Trial conditions are cleaner than real life. NCT04184622 ran 72 weeks under controlled everything, but kitchens still have holidays and missed workouts.
True. I use the 5/10/15 mg arms as context, not a template. Real life has too many variables.
That trial context is why NCT06897475 interests me: 200 people with type 2 diabetes on stable semaglutide or tirzepatide. Labs vs scale will be interesting.
And NCT07382024 is only 200 people, not recruiting yet. Different endpoint, but makes me want to track palpitations too.
I wish I’d tracked jeans size, not pounds—went down three sizes by week 60 while scale froze.
I wish I’d logged sleep and stress, not just weight. My loss slowed for six weeks around week 40, and I blamed the meds. Turned out I was averaging 5.5 hours and work stress was fueling 9 p.m. cereal.
When I bumped sleep to 7 and did a 10-minute walk afer dinner, the scale moved again. Numbers: waist down 5 inches by week 72, but sleep is the marker I’d track from day one.
Hot take: tracking everything made me obsessive; a monthly mirror photo and mood note was plenty.
I wish I’d tracked how often I said no to office birthday cake; that number is my real victory.
The one I'd redo is clothing fit. I bought the same style jeans one size down at week 20 and tried them on every Sunday morning, same time, no drama.
Weirdly more motivating than the scale — dropped two sizes between week 24 and week 60 while the scale only moved about 19 lbs that stretch. Now I just note which notch on my belt I'm on.
Weigh yourself the morning after a salty dinner and you'll swear the whole thng quit working.
Friday morning to Monday morning is my real tell. I logged it for three months out of curiosity and I'm up 2 to 3 lbs every single Monday, gone by Wednesday, always salt and Friday takeout and not enough water. Once I saw the pattern I stopped panicking on Mondays.
Honestly the Saturday step count predicts my Monday number better than anything I ate.
Honest fail: I tracked literally nothing until week 34, then found an old photo from a wedding and nearly fell over. What I'd do over is two things. First, one photo, same spot, same light, every 4 weeks — I have maybe six now and they show way more than any single weigh-in.
Second, a performance number that has nothing to do with the scale: I walk the same 2.2 mile loop and I timed it for months. Went from stopping twice on the hill to not stopping at all, and that happened during a stretch where the scale sat flat for like 14 weeks.
That flat stretch would've wrecked me mentally if the loop time wasn't written down somewhere. So my answer is photos plus one can-I-do-this-easier measure.
The thing I'd go back and track is one specific pair of jeans. Size 18 in week 4, size 12 by week 58, and here's the weird part: I stalled on the scale for eleven straight weeks in the middle of that and the jeans still kept geting easier to button.
If the scale had been my only scoreboard I'd have quit around week 40.
I wish I'd written down how many flights of stairs I could do without stopping. Week 8 it was two and I was winded at the top; by week 55 it was nine and I was just fine. My resting heart rate barely budged the entire time, which surprised me, so stairs ended up being the honest scoreboard.
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