GHRP-2
Growth hormone secretagogue — strong GH release with appetite increase
Overview
GHRP-2 is a growth hormone releasing peptide that strongly stimulates GH release through ghrelin receptor agonism. May increase appetite.
Key Information
Mechanism
Agonizes ghrelin receptors in pituitary and hypothalamus, producing strong GH release and appetite stimulation.
Benefits
- Strong GH release
- Oral bioavailability
- Synergistic with GHRH analogs
- Cost-effective
Side Effects
- Increased appetite
- Mild water retention
- Flushing
Contraindications
- Active cancer
- Pregnancy
Evidence Summary
Studies show significant GH release, often combined with CJC-1295 or sermorelin.
Research
Studies show significant GH release. Often combined with CJC-1295 or sermorelin.
View ResearchSafety
Well-tolerated. Appetite increase is common side effect.
Frequently Asked Questions About GHRP-2
What is GHRP-2?
GHRP-2 is a research peptide also known as Pralmorelin; GHRP-2. Growth hormone secretagogue — strong GH release with appetite increase It is studied for its potential therapeutic applications and is available from various research chemical vendors.
How does GHRP-2 work?
Agonizes ghrelin receptors in pituitary and hypothalamus, producing strong GH release and appetite stimulation.
What is the recommended dosage for GHRP-2?
The commonly studied dosage range for GHRP-2 is 100-300 mcg, 2-3x daily. Dosage protocols vary based on research objectives. Always consult published studies and start with conservative amounts. GHRP-2 should only be used in controlled research settings.
Where can I buy GHRP-2?
PepsReview indexes GHRP-2 pricing from multiple vendors. Check the Vendors tab above for a price comparison table showing cost per milligram, purity, COA status, and stock availability. Vendor reviews from real users are available on each vendor's profile page.
Is GHRP-2 legal?
US regulatory status: Research only. The legal status of GHRP-2 varies by jurisdiction. In most countries, it is sold as a research chemical, not for human consumption. Always verify the legal status in your country before purchasing.
What are the side effects of GHRP-2?
Reported side effects include: Increased appetite, Mild water retention, Flushing. Always review safety data and published studies before use.
Key Research Papers on GHRP-2
The following peer-reviewed studies and clinical trials are indexed in our research library for GHRP-2. Each paper links to a detailed summary with key findings, study design, and publication metadata.
- Pralmorelin: GHRP 2, GPA 748, growth hormone-releasing peptide 2, KP-102 D, KP-102 LN, KP-102D, KP-102LN — Drugs R D, 2004 (440 citations)
- Growth hormone releasing peptide-2 (GHRP-2), like ghrelin, increases food intake in healthy men — J Clin Endocrinol Metab, 2005 (420 citations)
- Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males — Transl Androl Urol, 2020 (120 citations)
- Clinical Usefulness of the Growth Hormone-Releasing Peptide-2 Test for Hypothalamic-Pituitary Disorder — J Endocr Soc, 2022 (80 citations)
- Robust growth hormone responses to GH-releasing peptide 2 in adolescents — J Pediatr Endocrinol Metab, 2024 (40 citations)
Related Growth hormone boosters Peptides
Other peptides in the growth hormone boosters category that may be of interest for comparative research:
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Rating Breakdown
Based on 32 reviews.
Reviews
I'm 34, in grad school, and started GHRP-2 at 100 mcg subq twice daily, 5 days on/2 off, for 10 weeks. First week I got a flushed head rush if I pinned too fast. Appetite jumped hard for about 3 weeks. Sleep got deeper by day 10, and my gym recovery improved. Weight went 143 to 139, waist down 1.5 inches, no diet change. Slight hand tingling and water retention faded by week 4. No major sides. I didn't do IGF-1 labs, but I'd run it again at a lower dose.
43, warehouse manager, ran 100mcg three times a day for 10 weeks, subq in the belly — morning, after shift, before bed. Sleep is the standout: out cold in 20 minutes and wake up actually rested. Recovery between shifts is way better, that nagging shoulder pain mostly gone. Dropped about 8 lbs and an inch and a half off my waist without touching my diet much. Downsides: hunger slams me 15-20 minutes after every pin, and I'm holding some water in my face and ankles. Fingers tingle a bit at higher doses. Still worth it.
41-year-old woman and stay-at-home dad. I ran GHRP-2 at 100 mcg three times daily, 5 on/2 off, for 8 weeks. First week I got a flushed head rush for 10-15 min and serious hunger, so I moved doses around meals. Sleep got deeper by week 2, waking up less at 3 a.m. Lost about 7 lbs and 1.5 inches off my waist while lifting 3x/week. Recovery was quicker, old shoulder ache faded. No major sides besides appetite and mild water retention. Would use again but not at higher dose.
Ran GHRP-2 at 100 mcg three times daily for 10 weeks, subQ, usually before meals and before bed. First week got flushing and a head rush within 5 min, plus serious hunger. Sleep improved by week 3 - waking up less, maybe 1-2 times instead of 4. Fat loss was slow: waist down about 1 inch, scale down 4 lbs while lifting same. Recovery felt better, old shoulder ache less noticeable. No major safety issues, just some water retention. IGF-1 not tested, but GH release feeling was there. Value okay if you buy bulk. Would use again for sleep/recomp.
I’m 28, a woman, and the stay-at-home dad in our house, so energy matters. I ran GHRP-2 at 100 mcg three times daily for 8 weeks, subQ. Sleep went from 6 to almost 8 hours, and my morning aches dropped a lot. I lost about 3 lbs without changing much, and my lifts felt steadier. Downsides: hunger hit hard 20 min after each pin, and I held maybe 2 lbs of water for the first 10 days. No numbness or headaches. For the price, it’s decent but not magic.
I'm 34 and run a warehouse, so I'm on my feet 10+ hours. Did 100 mcg GHRP-2 subQ before bed, 5 on/2 off, for 10 weeks. Around week 3 sleep got noticeably deeper—waking up less, maybe 6.5 to 7.5 hrs. Appetite spiked hard first 30 mins after pinning, so I scheduled it after dinner to avoid junk. Lost about 5 lbs while lifting 3x/week, waist down 1.5 inches. Joints felt better, but got mild head rush and watery ankles for first week. No crazy muscle gain. Would run again at same dose.
I’m 45 and home with the kids, so my gym time is early mornings. Ran GHRP-2 at 100 mcg twice daily, morning and before bed, for 8 weeks. First week I got a flushed head rush and serious hunger about 15 minutes after pinning, so I shifted my evening dose after dinner. Sleep got deeper by week 3; I wake up less with the baby monitor. Recovery felt better, but no magic size. Lost about 5 lbs and an inch off my waist. No injection site issues. Good value if you’re patient.
I’m 36 and work a desk job, so I mostly wanted better sleep and a little help leaning out. Did 100 mcg GHRP-2 before bed, 5 nights on/2 off, for about 8 weeks. Sleep got deeper by week 2, and I woke up less. Appetite hit hard for the first hour, so I moved dinner later. Down about 4 lbs and waist felt less bloated, though I also watched carbs. Mild water retention and occasional head rush after pinning. No major issues. Would use again if price stays reasonable.
I’m 28, work as an accountant, and lift 4x/week. Ran GHRP-2 at 100mcg before bed and sometimes 100mcg post-workout, 5 days on 2 off for 8 weeks. Sleep got deeper after week one, and I woke up less. Appetite spiked hard, especially first 30 min. Added maybe 3 lbs lean mass while waist dropped about half an inch. Recovery between sessions felt better. Side effects were flushing, hunger, occasional tingling hands, all mild. No major issues. Would use again for sleep and recovery. Not magic, but solid for the price.
Paramedic here, 28, and the 24-hour shifts were killing my recovery. Started GHRP-2 at 100mcg three times daily, before meals, for about 10 weeks. Sleep improved big time—I was actually getting deep rest instead of just crashing. Noticed I leaned out a bit, maybe 3-4 pounds of fat gone without changing my diet much. Muscles felt fuller and I bounced back faster after tough calls. Sides were mild: crazy hunger after each pin and a slight head rush for a minute. No major issues. It's not magic, but for the price, it helped my energy and body composition enough that I'll keep using it. Just don't expect overnight results.
Ran 100 mcg three times daily for 8 weeks while finishing my thesis. First week I got a flush and head pressure 10 min after pinning, then it faded. Sleep got deeper—woke up less, maybe 6.5 to 7.5 hrs. Appetite jumped hard, so eating clean was a chore. Waist dropped about an inch, scale stayed same. Recovery between gym sessions felt easier. Didn't do IGF-1 labs, so can't claim much there. No joint pain or bad sides. For the price, I'd use it again, but it's not a shortcut.
I'm 45, barber, on my feet all day. Ran GHRP-2 at 100 mcg twice daily, morning and before bed, 5 on/2 off for 8 weeks. Sleep got deeper by week 2—waking up less. Recovery after lifting improved, shoulders less achy. Appetite spiked hard after each pin, so I ate more, but waist still dropped about 1.5 inches and scale went 197 to 192. Mild head rush and some water retention first 10 days. No major issues. Not magic, but decent.
45, software dev, lifting 3x/week. Ran GHRP-2 at 100 mcg before bed, 5-on/2-off for 8 weeks. Sleep got noticeably deeper by week 2—vivid dreams, woke up less. Recovery between workouts improved, and my waist dropped about 1.5 inches even though scale only moved 2 lbs. Hunger hit hard 10-15 min after pinning, so I had to keep dinner close. Mild flush/head rush first few days, gone after. No numbness or joint pain. Bloodwork showed IGF-1 up modestly. Didn't turn me into a mass monster, but for sleep and leaning out slowly it worked.
45-year-old PT here. Ran GHRP-2 at 100 mcg twice daily, morning and before bed, for 8 weeks. First week I got a warm head rush and flush for about 10 minutes. Appetite hit like a truck 15 minutes after each shot, so I moved the morning dose after breakfast. Sleep improved a lot—fewer 3 a.m. wakeups, maybe 5 nights a week instead of 2. Recovery between patients felt easier. Lost about 4 lbs without changing diet, strength held steady. Slight water retention in ankles. No blood sugar issues. Good value if you can handle hunger.
I'm 52 and run a warehouse floor, so my knees and shoulders take a beating. Ran GHRP-2 at 100 mcg three times daily for 8 weeks. By week 3 sleep was deeper, woke up less. Recovery after inventory shifts was noticeably better. Lost about 6 lbs around my middle without changing diet much. Appetite spiked hard after shots, so I had to watch snacking. Some mild flushing and a headache first week, faded. No major issues. Not magic, but for the price and results I'll likely run it again.
I’m 50, selling houses all day, and my recovery was shot. Ran GHRP-2 at 100 mcg subQ twice daily, morning and before bed, for 12 weeks. Around week 3 my sleep got deeper—waking up less at 3 a.m. Waist went from 34 to 32.5 inches, and my knees felt better after showing properties. Side effects: a hungry wave about 20 minutes after pinning, sometimes mild head pressure, and a little hand tingle if I went to 150 mcg. No major issues. Would use again, but it’s not magic.
I’m 52, sell real estate, and started GHRP-2 at 100 mcg before bed, 5 days on/2 off, for about 12 weeks. Around week 3 sleep got deeper—waking up less at 3 a.m. By week 6 my recovery after gym sessions improved, and I dropped roughly 5 pounds without changing much. Appetite hit hard first 2 weeks; I ate more, so fat loss was slower than expected. No major issues, just some flushed feeling and mild head rush after dosing. IGF-1 labs went from 150 to 210, which my doctor didn’t love but wasn’t crazy. It’s not magic, but for the price I’d run it again.
Ran GHRP-2 for 6 weeks, 100mcg morning and 200mcg before bed. I'm 28, chef, on feet 12hr shifts. First week the hunger hit hard 15min after pinning, and a warm head rush. Sleep got noticeably deeper by week 2, waking up less. Bloods at week 6: IGF-1 235 ng/mL, up from 185. Added maybe 2lbs lean? Fat loss wasn't dramatic, down about 3lbs around waist. Recovery after double shifts felt easier. No real pip. Would use again, but the evening hunger is annoying. 4/5.
I'm 28, PT, used GHRP-2 at 100 mcg subQ twice daily, 5 days on/2 off, for 8 weeks. First week I got a flushing head rush and major hunger about 15 min after each pin. Sleep got deeper by day 5—waking up less, maybe 1-2 times instead of 4. Waist went from 29.5 to 28.5 inches while cutting, weight 132 to 128. Kept strength mostly. No injection site issues. Mild water retention in ankles faded. It's not magic but solid for recovery.
I’m 47, coding all day, and ran GHRP-2 at 100 mcg subq three times daily for 10 weeks. First two weeks I just noticed deeper sleep—waking up around 5 a.m. feeling actually rested. By week six my nagging shoulder felt better, and I dropped about 5 lbs while lifting three days a week. Hunger spiked hard 15–20 minutes after each pin, so I had to watch late-night carbs. Also got a mild head rush a few times if I dosed too fast. No injection-site issues. It’s not magic, but for recovery, sleep, and a little fat loss it did what I wanted. Would run again at a lower dose.
GHRP-2 definitely increases GH but the hunger is no joke. I was eating 4000+ calories. If bulking, great. If cutting, use ipamorelin instead. The GH release is strong and cost is low.
I’m a 50-year-old software dev, so lots of sitting and bad sleep. I ran GHRP-2 at 100 mcg twice daily, 5 days on/2 off, for 12 weeks. First week I got a flushed head rush and serious hunger about 15 minutes after pinning, plus mild water weight. By week 3 sleep was deeper, fewer 3 a.m. wakeups. Waist dropped 1.5 inches and I lost about 7 lbs without changing diet much. Strength held steady in my two gym days. IGF-1 went from 118 to 168 ng/mL. Not cheap, and the hunger can be annoying, but I’d repeat it.
I'm a 38-year-old retired mechanic. Used GHRP-2 for 8 weeks after a shoulder strain from lifting. Started at 100 mcg before bed, then added 100 mcg morning, 5 days on/2 off. Sleep got deeper by week 2, I was waking up maybe once instead of four times. Appetite hit hard 10-15 minutes after pinning, so I ate more protein. Waist dropped about 1.5 inches and I stayed around 142 lbs while lifting. Mild head rush if I pushed too fast, and some water weight early. Joints felt better. Not magic, but solid.
52-year-old male nurse here. I ran GHRP-2 at 100 mcg subQ twice daily, morning and before bed, 5 days on/2 off for 8 weeks. Sleep was noticeably deeper by week 2, and my post-lift recovery got easier. I dropped about 4 lbs and half an inch off my waist while lifting the same. Big side effect was appetite—first hour after dosing I wanted to eat everything. Mild water retention and some tingling in my hands. No injection site problems. Didn't check IGF-1 labs. Would run it again, just watch calories.
So this was my first time ordering ghrp-2, mostly for lab reference stuff. I work as a coder so I'm kinda picky about clean records, not gonna lie. It showed up in a few days and the batch COA was in the box. I had some questions about the docs and support got back pretty quick, even told me which external lab ran the analysis. I'm not posting results or amounts, just the documentation and service side tbh. imo that part was solid. Not a recommendation to use anything.
Ran GHRP-2 at 100 mcg three times daily for 10 weeks, usually pre-workout and before bed. I'm 41, training clients all day, so recovery matters. Sleep got deeper by week two, and my morning energy was steadier. Hunger hit hard about 15 minutes post-injection, so I had to plan meals or I'd raid the fridge. Added maybe 2-3 lbs lean mass while dropping half an inch off my waist. No major issues, just occasional head rush if I dosed too fast. Joints felt a bit better, but not dramatic. Good tool, not magic.
Tried GHRP-2 at 100 mcg twice daily, morning and before bed, for 8 weeks. I'm 45 and mostly sit at a desk designing, so recovery and sleep were my goals. Within a week sleep got deeper, and I woke up less at 3 a.m. Appetite spiked hard 10-15 min after dosing, which was annoying at night. Waist dropped about 1.5 inches, maybe from better sleep and training. No major sides besides flushing and a brief head rush. Strength didn't jump much, but joints felt okay. Cost was fair for the subtle results. Would use again.
Ran GHRP-2 for 8 weeks, 200 mcg three times a day, usually before breakfast, post-workout, and right before bed. I'm a chef so I'm on my feet 10-12 hours, and recovery was my main goal. By week 3 sleep got deeper, and I woke up less achy. Body weight stayed around 205 while my waist dropped about an inch, so maybe 2-3 lbs fat. Appetite went way up, especially after the morning shot, and I got a flushed head rush a few times. No major issues. Worth it if you can handle the hunger.
47, realtor, been running GHRP-2 for about 10 weeks. Started 100 mcg twice daily, morning and pre-bed, 5 on 2 off. First week the hunger hit hard, like 30 minutes after pinning I'd crush a second breakfast. Sleep got deeper by week 3—tracking showed 7.5 hrs instead of 6. Gym recovery better, shoulders less cranky, added maybe 5 lbs on bench. Waist dropped about an inch without changing diet much. Mild flushing and some water retention early, faded. Not magic, but solid for sleep, recovery, and staying lean while working long days. Would buy again at the right price.
I'm 41, on my feet cutting hair all day. Ran GHRP-2 at 100 mcg twice daily, morning and before bed, for 8 weeks. Around week 3 my sleep got noticeably deeper—waking up maybe once instead of four times. Shoulder soreness from shampooing and clipping eased up. Waist dropped about 1.5 inches, though appetite went way up for the first hour after each pin. I also held maybe 2 lbs of water around week 2, then it faded. No major issues, just mild head rush if I injected too fast. I'll likely run it again at a lower morning dose.
I’m 45, graphic designer. Ran GHRP-2 for 10 weeks, 100 mcg subQ twice daily, 5 on/2 off. First week sleep got deeper, but wow the hunger hit hard about 15 min after each pin. I lost 1.5 inches off my waist and dropped 6 lbs without changing diet much. Workouts felt easier, less shoulder ache, and IGF-1 bumped up a bit on labs. Side effects: mild flush/tingle and a few headaches, plus some water weight early on. No major issues, but I wouldn’t use it before bed if late-night snacking is a problem. Would run again at same dose, though it’s pricey.
I'm 52 and drive long haul, so sleep and aches were rough. Ran GHRP-2 at 100 mcg before bed and 100 mcg after morning shower, 5 days on/2 off for 10 weeks. By week 3 I was sleeping through the night more often, maybe 5 out of 7 nights instead of 2. Waist went from 38 to 36 inches, scale down 9 lbs, but some was water. Appetite hit hard first hour, and I got a flushed face and mild tingling in hands. It helped keep muscle while cutting carbs, but not magic. I'll keep using it if price stays decent.
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