Retatrutide: A Comprehensive Guide to the Weight Loss Drug

I'm 45 and drive a truck, so eating clean on the road is rough. My buddy and his daughter were on reta and I saw it work, plus the glucagon thing made me pick it over tirz. Started 2mg once a week, after 4 weeks went to 4mg. Twelve weeks in, down 19 pounds, waist lost about 3 inches. Appetite is way quieter, fasting glucose dropped around 12 points. Nausea and burps first two weeks, mild. Tirz is easier to explain to a doctor since it's approved, but reta's been good for me. Once-a-week shot fits my schedule.

41, sales rep. I went with retatrutide mainly because it was the first one I actually figured out how to get. I'd heard of tirzepatide later, and yeah, it sounds like less nausea and maybe stronger appetite suppression. But I was already pinning reta. Started at 2 mg weekly, moved up slowly to 8 mg over about six months. Down 34 lbs, waist lost 3 inches. Appetite is quiet most days. First few weeks I had mild nausea and some heartburn, now mostly fine. Energy dipped a bit. I'd still pick it again, though I get why others choose tirz.

I’m 28 and run a warehouse, so I’m on my feet all day. Started reta at 2mg/week, split into two 1mg shots, along with my tirz for about 8 weeks. The glucagon thing seemed to hit my visceral fat hard: down 14 lbs and 2 inches off my waist, less bloated in the gut. Appetite suppression was strong but not scary. First week I had mild nausea and heartburn, faded by week 3. Fasting glucose dropped a bit. I’m holding off on tesa until my back heals, then adding lifting and hiking. Price is steep, but I’d buy again.

Started retatrutide at 1mg weekly and worked up to 4mg by week 10. I'm 41 and on my feet all day managing a warehouse, so energy mattered. Down 22 pounds in 14 weeks, body fat dropped about 5% per my scale, and my A1c went from 5.8 to 5.4. Appetite is quiet now — I eat half what I used to and just stop. First month brought mild nausea and some sulfur burps, plus a tired stretch after each increase. Never missed a shift. My knees feel better too. If your body fat is high, don't overthink which fat is coming off — just get it off and the numbers follow.

I'm a 36-year-old marketer. Started retatrutide at 2mg weekly for 4 weeks, then bumped to 4mg for 8 more. Dropped 18 lbs, waist lost 2 inches. Appetite basically vanished. Nausea hit me the first couple days after each shot, kinda rough but faded. Energy up, A1c went from 5.9 to 5.4. Dosing once a week is simple. Not cheap, but I'd say worth it if you can afford it. No crazy side effects otherwise.

I’m 50, in marketing, and started retatrutide at 2 mg weekly. Over 6 months I titrated to 8 mg. Down 34 lbs, from 196 to 162, and my waist dropped 3.5 inches. Appetite is much quieter; I finally stopped afternoon vending-machine runs. A1c went from 5.9 to 5.4 and my BP is down about 8 points. Main side effects: mild nausea for a day after each increase and some constipation. Weekly injection is easy. It’s not magic—protein and walks still matter—but I feel steadier and lighter.

55-year-old chef here, on my feet 10 hours a day. I ran reta for about 5 months: 2 mg weekly for the first month, then 4 mg, now holding at 6 mg. Down 34 lbs, waist went from 42 to 37 inches. The biggest change was around my middle and liver area; I assume visceral fat dropped along with overall weight. Appetite is way quieter, and my A1c fell from 6.1 to 5.6. Nausea and sulfur burps hit for a day or two after each shot, plus some constipation. Tesa wouldn't have done this for me since it doesn't really cause weight loss. I'll stay on it.

I'm 55 and work a desk job. After tirzepatide stalled, I tried retatrutide, 8 mg once weekly for about 6 months. Down 26 lbs (12%), waist lost 4 inches. Triglycerides fell from 190 to 115, LDL 150 to 100, hs-CRP 4.5 to 1.9, and my eGFR bumped up a bit. Blood pressure went from 138/88 to 122/78. Appetite is quieter, but I get nausea for a day after shots. Resting heart rate rose about 10 bpm, and it costs way more. Long-term safety still worries me. I wanted the newer option, but I'd call it a solid 4.

I’m 41 and drive long haul. I picked retatrutide first because it was the one I kept hearing about—didn’t realize tirzepatide was even an option until after I’d started. I began at 2 mg weekly, went to 4 mg after a month, and I’ve been at 6 mg for about 12 weeks. Five months total. Down 38 lbs, 212 to 174, and my jeans dropped two sizes. Appetite is way quieter, but I can still eat. Mild nausea and constipation early on, gone now. A1c went 5.8 to 5.4. I’d stay on reta, no regrets.

I'm 31, retired mechanic after a back injury. I never stacked peptides or even took regular meds, so reta alone was a big step. Did 2 mg once weekly for 4 weeks, then 4 mg weekly for 8 weeks. Down 17 lb, waist from 38 to 35.5 in. Visceral belly got softer and less bloated, not shredded but noticeable. Appetite was quiet for 2-3 days after each shot. Weeks 1-3 I had nausea, sulfur burps, and some fatigue, then mostly fine. Fasting glucose went 104 to 91, A1c 5.6 to 5.3. No stacking, and I'd call the visceral fat loss modest but real.

I'm 55 and drive long haul. I started retatrutide because it was the first peptide I found a way to get, not because I compared it to tirz. I began at 1 mg weekly, went to 2 mg by week six. Twelve weeks in, I'm down 19 pounds, 214 to 195. Appetite is much quieter but I can still eat. Mild nausea and tiredness for a couple days after shots, gone by week three. My fasting sugar readings look steadier. I'd pick it again.

I’m 50 and drive long haul, so eating right is tough. Started retatrutide at 2 mg weekly, went to 4 mg, then 6 mg over about four months. Weight went 268 to 243, waist 46 to 42, and my body fat dropped roughly 5%. Appetite was way down, so I stopped hitting vending machines and truck stop fried food. Mild nausea and sulfur burps early on, plus some constipation, but it passed. A1c fell from 6.1 to 5.6 and triglycerides from 190 to 130. If you’re carrying a lot of extra fat, don’t overthink which fat is going first—5% body fat loss shows up and helps your labs.

Started retatrutide at 2mg weekly, bumped to 4mg after a month. Been on it about 14 weeks now. Down 18 lbs, from 212 to 194. Appetite is way down, I actually forget to eat lunch sometimes. My A1c dropped from 5.9 to 5.4. Body fat scale says about 3% less, though who knows. Only side effects: mild nausea first two weeks and some sulfur burps if I eat greasy. Energy is better. Dosing once a week is easy. Not cheap but works. Would recommend if you can afford it.

I'm 42, work as an engineer, so I tracked everything. Started retatrutide at 2mg weekly, titrated up to 8mg over 12 weeks. Stayed there for 5 months. Lost 31 lbs (14 kg), waist down 4 inches. Appetite is basically gone – I have to remind myself to eat. Blood sugar improved (A1C from 5.8 to 5.4). Nausea hit hard on shot days for the first month, then faded. Some fatigue. Dosing once weekly is super convenient. Not cheap, but it works. Would recommend if you can handle the initial side effects.

43yo trainer here. Ran retatrutide 2mg twice weekly for 10 weeks, stacked with 5mg tirzepatide weekly. Lost 13 lbs (205 to 192), waist dropped just over 2 inches, and my visceral fat scan estimate fell from 1.4 to 1.1. Appetite was crushed first 3 weeks - mild nausea and some sulfur burps, but nothing unmanageable. Energy stayed decent for hiking; lifting stalled while my back was jacked, so I'm restarting resistance work now. I also have tesamorelin waiting, but I want more info before adding it. Split dosing seemed smoother than one weekly shot. Not a miracle, but the midsection change is real.

41 yr old accountant, never really took meds before. I was nervous about stacking anything, so I ran retatrutide solo. Did 2 mg once a week for 4 weeks, then 4 mg weekly for another 8 weeks. Down 15 lbs, waist dropped about 1.5 inches, and my appetite is way quieter. Early on I had mild nausea and constipation, but it faded by week 3. No major issues. Not a miracle, but for modest visceral fat loss without adding anything else, I'm pretty happy. Still have some belly fat, but clothes fit better.

52, graphic designer, desk job. I’ve been on retatrutide about 10 weeks, ramping from 2mg to 4mg weekly, split into two shots with my tirzepatide because the glucagon part seemed to target my visceral fat. Down 11 lbs and my waist is about 1.5 inches smaller—my jeans fit again. Appetite is way quieter, no more afternoon vending machine raids. Some mild nausea and sulfur burps the first few days after each bump. My fasting glucose is steadier. I’m holding off on adding tesamorelin until my back issue settles, then resistance training and hiking. Good so far.

I'm 45, personal trainer. Ran retatrutide 12 weeks, started 2mg weekly, went to 6mg. Weight went 212 to 189, waist down 3.5 inches. My smart scale's visceral estimate fell from 14 to 11. Appetite was very blunted; some nausea and sulfur burps around 4mg, gone by week 8. Strength held okay, maybe lost a bit of arm size. Liver enzymes dropped into normal range. I tried tesamorelin before and it didn't move scale/visceral much for me. Reta's bigger effect came mostly from actual weight loss, maybe extra liver/belly help. Would use again.

I'm 38 and cut hair all day, so standing was killing my knees. My buddy and his girl were on reta, and I watched them shrink. That sold me. I also liked that it hits the glucagon receptor, not just GLP-1/GIP like tirz. Tirz is more familiar though—my doctor knows it, and it's approved, so less explaining. I started at 2mg weekly, went to 8mg by month four. Down 22 pounds. Nausea hit me the first two weeks but faded. Injection site got red once. Appetite is way down. A1C dropped from 5.8 to 5.4. I'd say it's worth it, though still experimental.

45yo ex-athlete, spreadsheet nerd. Ran retatrutide 2mg weekly for 4 weeks, then 4mg for 8 more. Started at 218 lbs, 24% BF; now 199 lbs, 19% BF. Waist down 3.5 inches. Appetite was noticeably blunted after week 2, so I hit protein and lifting harder. Mild nausea first few days after each bump, some constipation. Bloodwork improved: A1c 5.7 to 5.4, trigs down 45. If you're carrying extra fat, don't overthink which fat you're losing — a 5% BF drop changes the mirror and biomarkers. I'll keep going.

I'm 50, run a warehouse. I picked retatrutide after watching a buddy and his kid drop weight on it—seeing that beat any research. The extra glucagon piece made it more interesting to me than tirz. Started 1 mg weekly, now at 4 mg after 14 weeks. Down 23 lbs, waist lost 3 inches, appetite way quieter. Mild nausea first few days after shots and some fatigue, nothing that stopped work. My A1c bumped from 5.9 to 5.5. Tirz seems easier because doctors know it and brand names ring bells, but reta has been solid for me.

My oldest kid mentioned retatrutide before I'd ever heard of it, so I spent a couple weeks reading up before I ordered anything. Started at 2 mg and went up every four weeks; I've been sitting at 12 mg for about two months now, 26 weeks total. Down 34 lbs, 198 to 164. Appetite is basically quiet, which matters a lot when I'm living out of gas stations between sales calls. Only side effect was some mild queasiness the first week after each increase. My husband runs the same schedule and he's had nothing either. A1c went 5.8 to 5.3. Pricey, but it's working.

I'm 55, work as a chef, started retatrutide at 2 mg/week and slowly went up to 8 mg over about 6 months. Starting weight 242 lbs, 28% body fat; now 216 lbs and around 23%. My waist dropped 4 inches and my A1c went from 6.1 to 5.6. Appetite is way quieter, which helps when I'm tasting sauces all shift. Mild nausea and constipation for the first few weeks, then mostly fine. If your body fat is higher, don't obsess over what kind of fat you're losing—5% body fat down shows up in the mirror and bloodwork.

I'm a 41-year-old paramedic, started retatrutide at 2mg weekly. After 3 months, titrated to 8mg. Lost 38 lbs in 6 months (210 to 172). Appetite is gone, I have to remind myself to eat. A1c dropped from 5.9 to 5.4. Side effects: nausea first two weeks after each dose increase, some constipation. Injection is easy. My energy is better, but I did have one episode of palpitations that scared me. Still worth it.

Started retatrutide in January at 2mg weekly, then bumped to 4mg after a month and stayed there for 12 more weeks. I'm 47 and home with two kids, so routine is chaotic. Weight went from 247 to 223. Body fat dropped from 33% to 27%, which shocked me. I stopped worrying about whether it was visceral or subcutaneous—at that level, a five-point drop is obvious in the mirror and my A1c fell from 5.8 to 5.4, triglycerides down 40 points. Mild nausea on shot day for first two weeks, some constipation. Worth it.

I'm 28, work in sales, and was new to peptides. I ran retatrutide solo for 10 weeks. Started at 2 mg/week, bumped to 4 mg by week 5, then 6 mg. Didn't stack anything. Lost about 12 lbs and my waist dropped 1.5 inches. Appetite was way down, especially at night. Mild nausea first two weeks and some fatigue, but it passed. Visceral fat is hard to measure, but my belt is looser and my stomach looks flatter. Not a crazy transformation, just modest steady progress. I'd use it again.

I’m 52, run a small bistro kitchen, and never really took meds daily. Started retatrutide alone because I wasn’t ready to stack. Did 2 mg weekly for first 4 weeks, then 4 mg for another 8 weeks. Down 14 lbs total, waist about 2 inches smaller, and my morning glucose dropped from 108 to 96. Appetite quieter, especially after shifts. Nausea first two weeks and some sulfur burps, but nothing that kept me off my feet. Visceral fat? I can’t measure exactly, but my pants fit much better. Not dramatic, but real. I’d say modest visceral loss is possible solo.

38F, office job, started reta in Feb for weight loss. Did 2 mg weekly for 4 weeks, then 4 mg for 8 weeks. Down 23 lbs (234 to 211), waist lost 3 inches. Appetite vanished fast, which made calories easy to cut. Nausea and heartburn hit mostly the day after shots, but they faded by week 3. My ALT also dropped from 38 to 24, so belly/liver fat clearly improved. I think most of that came from the weight loss, with maybe a little extra midsection help. Mornings were my best time to dose. I’d stay on it.

I'm 41, run a warehouse floor all day, started retatrutide at 218 lbs and about 38% body fat. Did 2 mg weekly for a month, then 4 mg for eight more. Down 23 lbs and 6% body fat; lost 3 inches off my waist. Appetite was way down, sometimes too much. Mild nausea and constipation early on, gone by week six. A1c went 5.8 to 5.4 and triglycerides dropped. I stopped stressing over whether it was visceral or under-skin fat—at my starting level, a solid body fat drop changed how I look and my labs. Worth it.

55-year-old physical therapist here. I was new to peptides and nervous about stacking, so I ran retatrutide solo. Started at 2 mg weekly for four weeks, then 4 mg weekly for eight more. Stayed on 4 mg. Lost 10 lbs (212 to 202) and waist dropped from 40.5 to 38.5 inches. Appetite was noticeably quieter, but no magic. Mild nausea first two weeks and some constipation; both faded. Fasting glucose went 103 to 94, BP 132/84 to 126/80. I kept lifting and walking. Visceral fat change seemed modest but real. Weekly subq injection was easy. No stacking, no Tesa.

55, graphic designer. Switched to retatrutide after tirzepatide stalled. Did 8 weeks at 2mg then 4mg then 8mg weekly. Lost 16 lbs, visceral fat down 11% on DEXA. Triglycerides 220→150, LDL 155→105, hs-CRP dropped a lot. BP 138/88→122/78. Kidney eGFR improved from 72 to 84. But resting heart rate went 60→76, and I get queasy for 36 hours post-shot. Cost is brutal. Wanted the shiny new thing. Works, but monitor your heart.

Started retatrutide at 2 mg weekly for four weeks, then 4 mg weekly for another eight. I'm 52, work as a physical therapist, so I notice joint stress and body comp. Dropped 19 lbs and about 5% body fat by DEXA. Not dramatic scale noise, but shirts fit better and my fasting glucose fell from 104 to 91. Appetite was much quieter; I still ate regular meals. Mild nausea first two weeks, some sulfur burps if I ate late. At higher body fat, don't obsess over which fat type is going—5% BF loss changes how you look and moves labs. I'll stay on 4 mg.

I'm 42, work in marketing, so I sit a lot. Started at 2mg weekly for 4 weeks, then 4mg, now on 8mg for 3 months. Down 26 lbs in 5 months (215 to 189). Appetite is way down, I actually forget to eat. Nausea hit me hard the first two weeks after each bump, but now it's mild. Energy is better, my A1c went from 5.8 to 5.3. Only real downside is cost and some constipation. But it works.

I’m 41 and drive long haul. I started retatrutide at 2 mg once a week, went to 4 mg after a month, then 6 mg by month three. Five months in, I’m down from 209 to 182. Appetite is way quieter, so I’m not grabbing jerky and soda at every stop. First few weeks I had mild nausea and constipation, plus some fatigue. It eased by week four. I didn’t really know tirzepatide was an option back then; reta was just what I found first. I’d still pick it again because it fits my schedule and I feel steadier.

My oldest brought up retatrutide, and after a lot of digging I decided to try it. I'm a 45-year-old trainer, so I tracked everything. Started at 2 mg weekly, moved up slowly, and stayed at 12 mg for the last 10 weeks. That's about 7 months total. Down 31 lbs, waist lost 5 inches, and my appetite is way more manageable. A1c went from 5.7 to 5.3. My wife and I both had almost no side effects—just some mild queasiness around the 8 mg bump for a few days. Energy in sessions stayed solid. It isn't cheap, but it's been worth it for me.

I’m 38, a sales rep, on my feet and driving a lot. Started reta because it was the first one I learned about; by the time I figured out tirz was easy to get, I was already pinning. Did 2 mg weekly for 4 weeks, then 4 mg, now 6 mg for about 5 months. Down 24 lbs, waist lost 3 inches, appetite is way quieter. Mild nausea and constipation early, some fatigue on shot day. It hasn’t been perfect but I’d rather not switch. Curious why others pick tirz, but reta works for me.

I'd never heard of retatrutide until my older sister brought it up, then I went down a research rabbit hole. My wife and I both started at 2 mg weekly, bumped to 4, 8, then 12 mg over about five months. I'm a sales rep, so lots of drive-thrus and airport food, and this finally quieted the constant snacking. Down 31 lbs, from 194 to 163, and my A1c dropped from 5.8 to 5.4. Appetite suppression is strong but manageable. Side effects? Honestly almost none - maybe a little tired the day after the shot. Up to 12 mg with no bad effects, which feels lucky.

34M dev here. Switched from tirz to reta for the last 7 months, 2mg weekly then 8mg. Down 31 lbs (206 to 175), waist dropped 4.5 inches, triglycerides 142 to 74, LDL 138 to 88, hs-CRP 4.1 to 1.3, BP 134/88 to 120/78. Appetite suppression is strong; visceral fat and liver numbers clearly better than tirz for me. Downsides: resting HR went 57 to 71, some nausea, and it costs about $450/month. Long-term safety still unknown. I wanted the newer thing, and I'd do it again.

I'm 41 and lifeguard year-round, so I needed energy, not a crash diet. Started retatrutide at 2 mg weekly in March, went to 4 mg, now 6 mg for eight weeks. Down 31 lbs, 178 to 147. Waist went 34 to 29 inches. Appetite is quiet; I actually finish one plate. Mild nausea and sulfur burps first two weeks, some constipation, and a tired day after injections. A1c 5.6 to 5.2. I feel steadier on long shifts, no dizzy spells. It's not cheap, but the weekly shot is easy. I'd recommend it if your doctor agrees.

31M, office job. Ran retatrutide 12 weeks, titrated 2mg to 6mg weekly. Down 24 lbs (248 to 224), waist -3.5 inches. Appetite was very low, maybe too low some days. Resting heart rate climbed ~10 bpm, and I had mild nausea weeks 1-3. Labs: triglycerides -35%, LDL -18%, hs-CRP halved, BP down ~8/5. Kidney numbers improved slightly. Cost hurts, long-term safety still unclear. Compared with tirz, fat and metabolic results seem stronger, but side effects and price are worse. I wanted the shiny new thing, and it delivered.

My oldest son mentioned retatrutide, and I’d never heard of it or any similar peptide. I did my own research and started at 2 mg per week. Six months later I’m at 12 mg weekly. Down 34 pounds, from 238 to 204. Appetite is way quieter, I eat about half what I used to, and my A1c dropped from 6.1 to 5.5. My wife and I both had no nausea, cramps, or fatigue even at 12 mg. Weekly injection fits my sales travel. Cost is the main downside.

I'm 55, a graphic designer, and I picked retatrutide mostly because it was the first peptide I learned how to source. By the time I understood tirzepatide was even an option, I was already dosing reta. Started at 2 mg weekly for a month, then 4 mg for two months. Down 19 lbs, about 2.5 inches off my waist. Appetite is very quiet, but I get waves of nausea if I eat too much fat. Mild constipation, manageable with water and magnesium. Energy and labs improved. I'd stay on it. Dosing once weekly is easy.

55, graphic designer. Switched from tirz to reta. Titrated 2mg to 8mg over 12 weeks. Down 22 lbs, waist lost 3 inches, appetite almost nonexistent. Trigs fell 55, LDL 20, hs-CRP cut in half; eGFR improved a bit and BP down 7 systolic. Side effects: resting HR jumped ~10 bpm, mild nausea early, and cost stings. Long-term safety still a question mark. I wanted the newer thing, and for me the fat loss and labs were clearly better than tirz. Not perfect, but I'm staying on it.

34, retired mechanic here. Been on reta about 5 months. Started at 2mg once a week, bumped to 4mg, now at 6mg. Down 38 lbs, 248 to 210. Appetite is much quieter but not gone. First few weeks I had nausea and heartburn, plus cold hands. Mostly faded by week 6. I picked it because a close friend and his daughter were on it and I saw their results firsthand. The glucagon receptor part made it more interesting to me than tirz. Tirz is more familiar and easier to explain to a doctor, but I wanted that extra mechanism. Waist is down 3 inches. Energy is decent. No regrets.

I'm 50, desk job. Started reta because a buddy and his daughter had great results. The glucagon hit was a draw over tirz. Did 2mg weekly, bumped to 8mg over 10 weeks. Down 18 lbs, appetite crushed. Mild nausea first two weeks, some tiredness. My doctor was skeptical since it's not approved like tirz, but my A1c dropped a bit. Once weekly shot is easy. Overall solid, but explaining it to people is annoying.

I’m 33 and very into skincare—topicals, Botox, the works—but pretty conservative with systemic meds. I didn’t want to stack anything yet, so I tried retatrutide solo. Did 2 mg weekly for 4 weeks, then 4 mg for 8 weeks. Down 13 lbs and my waist dropped almost 2 inches; my midsection feels less dense, which is the visceral fat I was worried about. Appetite was noticeably quieter. Mild nausea and some burping the first two weeks, nothing after. No skin issues or weird interactions with my usual routine. It’s not dramatic, but for no stack, I’m happy.

I’m 29F and have tried two other peptides before this one. I started reta at 2 mg/week, split into 1 mg twice weekly, and kept my tirz at 5 mg. Did that for 10 weeks. Appetite dropped within 3-4 days. I’m down 13 lbs and my waist is about 2 inches smaller; the visceral fat around my lower belly finally moved. Mild nausea and some fatigue the first two weeks, plus heartburn if I dosed too close together. I have tesa waiting, but my back is still cranky, so I’m holding off until I can do resistance training and hiking again. Overall worth it.

I'm 52 and drive for a living, so sitting all day didn't help. I ran retatrutide at 6mg for 3 months and ended up down 33 lbs. Not gonna lie, first couple weeks I was queasy and tired, but it eased up. tbh the appetite thing was strong, I had to remind myself to eat. imo it was worth it for me but I'm not a doctor and this is just my experience. No crazy sides after the start, just some weird burps and low energy here and there.

I'm a 43-year-old software dev, so I over-research everything. I picked retatrutide after watching a friend and his daughter use it—seeing their progress beat any online homework. The glucagon-receptor piece intrigued me, and it felt like a bigger step than tirzepatide. I started at 2 mg weekly, went to 6 mg by week 12. Down 17 lbs, waist down 2 inches, appetite much quieter. Fasting glucose dropped about 10 points. Mild nausea and constipation early on, mostly gone now. A buddy stayed with tirzepatide because the brand name is familiar and doctors already approve it; reta takes more explaining. I get that, but I'm happy here.

55 yo trucker here. Ran reta about 12 weeks, split 2mg Mon/Thu with my tirz. Started 1mg/week, went to 4mg total. Down 23 lbs, waist 3 inches, belly gut a lot flatter. Appetite quiet, but some nausea and sulfur burps first few weeks, and heartburn on drive days. Energy okay, lifting in truck stop gyms and hiking on resets now. Had a back issue that sidelined me, so I paused. Labs improved, A1c 6.1 to 5.6. Not cheap, but it works. I'd buy again.

34-year-old teacher here. I wanted visceral fat help without stacking anything. I started retatrutide alone at 2 mg once weekly for 12 weeks. Appetite dropped by week 2, so I ate way less at night. Down 14 lbs, waist from 38 to 36 inches, and my fasting glucose went from 101 to 92. Mild nausea and constipation first two weeks, then mostly fine. No crazy fatigue. I'm not saying it's a miracle for visceral fat, but I saw a modest change, especially around my midsection. If you're new and don't want to stack, this felt manageable and worth it.

I'm 47 and teach middle school, so I needed something simple. I started retatrutide at 2 mg weekly for a month, then 4 mg for eight weeks. Down 22 lbs, waist went from 39 to 36 inches. My fasting glucose and ALT improved, and my doctor said liver fat looked better on ultrasound. Appetite was way quieter. BP came down a bit. Main issues: nausea for a day after each shot, sulfur burps, and some fatigue. I lost a little muscle too, so I'm lifting and eating more protein. Weight loss itself does most of the visceral fat work, but this seemed extra helpful around my belly.

I got retatrutide and the COA named the outside lab that ran the test. The cert matched the vial, which is the main thing I looked at. I'm not naming any amount and I'm not claiming any health outcome. No side effects to report from my end. The process was straightforward and the paperwork lined up. Tbh that's all I can say. I'm 52 and teach, so I just wanted the cert to match. It did. Not gonna lie, that gave me some peace of mind. Imo that's worth noting.

I'm 41, an accountant, and chose retatrutide for the glucagon effect on stubborn visceral fat. I did 2 mg twice weekly with my tirz for 10 weeks. Down 14 lbs and my waist lost about 1.5 inches; appetite got much quieter by week two. Mild nausea and shot-day fatigue, nothing bad. I ordered tesamorelin too but I'm letting it sit until my back settles, then I'll add resistance training to hiking. Reta feels worth it for midsection changes.

45, grad student. I did 2 mg weekly retatrutide for four weeks, then 4 mg for eight. Lost 18 lbs in 12 weeks; waist down 3 inches. My appetite was way quieter, and my fasting glucose and liver enzymes improved. I did get nausea and some fatigue the first two weeks, which faded. Visceral fat definitely dropped, but I think most of that came from overall weight loss. The glucagon part may help liver fat extra. I tried tesamorelin before and it didn't move the scale, so reta had a much bigger effect. Weekly shot is easy, though pricey.

41-year-old sales rep here. Started retatrutide at 2 mg weekly, moved to 4 mg after four weeks, then 6 mg by week ten. Stayed there for about five months. Down 27 lbs, from 232 to 205. Appetite was quieter, but not totally gone. Heartburn and some nausea on shot day, plus a little fatigue after dose bumps. Good energy between trips. Bloodwork showed A1c dropped from 5.9 to 5.5. I picked it first because it was the one I stumbled on, not because I compared everything. Would do it again.

Down 28 lbs in 4 months. The weight loss is unmatched but increased heart rate is a real side effect. Also noticed it blunted my dopamine - lost interest in unhealthy habits which was actually positive.